Speaker
Francesco Romano
Description
See the full Abstract at http://ocs.ciemat.es/EPS2018ABS/pdf/P2.2010.pdf
Geant4 Monte Carlo simulations for the optimization of spatial dose
distributions of clinical relevance with laser-driven proton beams.
F. Romano 1,2, F. Schillaci 3, G. Milluzzo 2,4, J. Pipek 2, A. G. Amico 2, G. Cuttone 2, G. Korn
3
, G. Larosa 2, R. Leanza 2,5, D. Margarone 3, G. Petringa 2,5, A. Russo 2, V. Scuderi 2,3, G. A.
P. Cirrone 2.
1
National Physical Laboratory, CMES - Medical Radiation Science, Teddington, UK
2
INFN, Laboratori Nazionali del Sud, Via Santa Sofia 62, Catania, Italy
3
Institute of Physics ASCR, v.v.i (FZU), ELI-Beamlines project, 182 21 Prague, CZ
4
School of Mathematics and Physics, Queen’s University Belfast, Belfast, UK
5
Università di Catania, Dipartimento di Fisica e Astronomia, Via S. Sofia 64, Catania, Italy
The main purpose of this work is to quantitatively study the possibility of delivering dose
distributions of clinical relevance with laser-driven proton beams in order to investigate the
feasibility of these beams for multidisciplinary applications, included the medical ones. In
particular, a Monte Carlo application has been developed with the toolkit Geant4 aiming to
simulate the ELIMED (MEDical and multidisciplinary application at ELI- Beamlines) beam
line which is being installed at ELI-Beamlines in Prague (CZ) [1]. The beam line will be used
to perform irradiations for multidisciplinary studies, aiming to demonstrate the possible use
of optically accelerated beams for therapeutic purposes [2]. The ELIMED application,
developed with the Geant4 code, accurately simulates each single element of the beam line,
designed to collect the accelerated beams and to select them in energy, and it has been
validated with reference transport codes [3]. The final aim of this work is to try to
quantitatively answer the question if such kind of beam lines, and specifically the systems
developed for ELIMED in Prague, will be actually able to transport beams not only for
multidisciplinary applications but also for delivering dose patterns of clinical relevance,
which are worth to explore possible medical applications. On this regard, an original
approach for actively shaping, through the magnetic energy selection system, depth dose
distributions to achieve clinical spread out Bragg peaks will be also presented.
[1] J. Pipek et al., J. Instrum. 12 (03) (2017) C03027
[2] F. Romano et al., Nucl Instrum Methods Phys Res Sect A (2016); 829:153-158
[3] G. Milluzzo et al., Nucl Instrum Methods Phys Res Sect A (in press)
